• Spalding Professor of Chemistry

    Gilmer Hall, 207
    (434) 223-6283
    hsipe@hsc.edu


  

Education

Visiting Scientist, National Institute of Environmental Health Sciences, Research Triangle Park, 1987-88, 1996, 2002-2003, 2009-2010
Visiting Professor, Univ. of Alabama-Tuscaloosa, 1980-81
Ph.D., University of Wisconsin-Madison, 1969
B.S., Juniata College, 1962

Teaching Interests

General, physical, and analytical chemistry
Chemical Instrumentation
Medicinal chemistry: Chemistry 332 and Toxicology: Chemistry 331  for science majors
Chemistry for non-science majors:  Chemistry 105 "Toxic Chemicals in Society"
Western Culture: Western Culture 103 (now 102)
History and philosophy of science

Research Interests

Research in physical chemistry and physical biochemistry with undergraduate coworkers
Experimental techniques and instrumentation in electron spin resonance  (ESR) spectroscopy 
ESR studies of Free radical metabolites of xenobiotic compounds (xenobiotics are chemicals foreign to an organism's environment)
ESR Studies of chemically- and biochemically-generated radicals of pharmaceutical and nutraceutical compounds
Computer-assisted analysis and simulation of ESR spectra

Research Interests and potential topics for students

An umbrella description of my research interests might be "Studies of free radicals involved in antioxidant properties of drugs, food additives, and phytochemicals." These studies are based on electron spin resonance (ESR) spectroscopy, and my recent advanced lab students have been investigating compounds such as BPA (and related molecules), curcumin, amodiaquine, parabens, flavanols, etc.